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Two case studies of a laser-resistant port-wine stain (PWS) previously treated with pulsed dye laser and maximum spot size of 10 mm. Marked lightening of the PWS with no epidermal injury was observed in a skin type III male and laser-resistant PWS improvement in a skin type IV male, following 2 monthly Vbeam Prima treatments with the large 15 mm spot size.

28 women with photodamage underwent a picosecond laser treatment with the Resolve 1064 nm handpiece, using low energy fluence of 1.1 J/cm2 or high energy treatment (2.1 J/cm2). High energy group showed significant improvement with a more pronounced effect on facial skin than low energy treatments. Histopathological examination of biopsies at 3 weeks’ post-treatment showed a marked elevation in collagen type III expression antibodies in the high fluence group.

18 postmenopausal women with atrophic vaginitis received 3 monthly CO2RE Intima laser treatments to the vulva and vaginal canal. Restoration of normal or near‐normal vaginal health index (VHI) following treatment in the recently menopausal (1–3 years) cohort was significantly greater than that of the >3 years postmenopausal population. Female Sexual Function Index (FSFI) was significantly improved at the 12-month follow-up.