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As we age, skin loses its elasticity. 3 key reasons facial wrinkles and the appearance of cellulite increase(3):
Icon demonstrating that collagen levels decrease every year, resulting in an increase of facial wrinkles and appearance of cellulite.

Collagen levels decrease every year

Icon demonstrating that elastin production stops over time, resulting in an increase of facial wrinkles and appearance of cellulite.

Elastin production stops

Icon demonstrating that hyaluronic acid diminishes over time, resulting in an increase of facial wrinkles and appearance of cellulite.

Hyaluronic acid diminishes

Why Consider the Profound System?

Patients seek treatments that:

  • Are less painful and invasive than surgery
  • Offer an alternative to the use of toxins and fillers 
  • Require more manageable downtime 

The Profound® system provides a non-surgical alternative to address aging skin:

Using radiofrequency (RF) injectable energy, it provides long-lasting facial wrinkle reduction and improves the appearance of cellulite.4,5

Key Benefits of Profound RF Microneedling

The Profound system can help your practice: 

Fill the treatment gap that exists between dermal injectables and invasive surgery 

  • Adopt new patients in advance of surgery 
  • Retain existing patients who are not ready for surgical procedures 
  • Increase revenue with complementary treatments and future procedures 

Bottom line: 

The Profound system enhances aesthetics practices by providing a clinically proven, non-surgical, single-treatment procedure1,4,5 that requires less practice expense and patient downtime.

  • "Profound takes us to the next level…we deliver the RF energy directly to the reticular dermis, which is the target. We also have real-time feedback of target tissue temperature and delivered energy, so we can control how much energy we deliver, as well as achieve and maintain a therapeutic temperature level exactly where the energy is supposed to go. In my experience, this device is by far the most effective for minimally invasive dermal volumizing in a single treatment."
    Macrene Alexiades-Armenakas, MD, Ph.D
    New Haven, CT, USA
  • "In my practice, Profound is our preferred and most effective treatment for skin volumizing and lifting of the face and neck. An additional benefit of the Profound treatment is the overall improvement in skin quality, and a noticeably greater elasticity of the skin."
    Leyda Bowes, MD
    Dermatologist Miami, Florida, USA
  • "Profound causes very precise dermal injuries that arouse an anabolic wound healing response which stimulates the growth of collagen and elastin in a way that we’ve not seen before. We are consistently able to create younger, more elastic skin, in addition to improving volume. Even patients in their thirties could periodically turn back the clock on early laxity and loss of volume."
    Andrea Willey, MD
    Laser and Skin Surgery Center of Northern California Sacramento, CA
  • "We all know that the key to maximizing results is the ability to maximize the delivery of adequate treatment energy to achieve the desired effect. It’s easy for us to tell how much energy we’re using, but how do we know if it is being delivered to the target, and if it is enough to help us achieve the desired result? Profound is able to answer these questions, so users can rely on more than reasonable expectations."
    James Newman, MD
    Facial Plastic Surgeon, Medical Director, Premier Plastic Surgery Palo Alto and San Mateo CA

Profound RF is a One-of-a-Kind Wrinkle & Cellulite Treatment System

8 facts that make this a one-of-a-kind, must-have system.

  1. Clinically proven to create all 3 skin fundamentals: up to 5x more elastin, up to 2x more collagen, and increased hyaluronic acid.1,4
  2. First and only RF microneedling device with FDA clearance for face and body4 
  3. Just one non-surgical treatment required to achieve lasting results2,4,5,6 
  4. 100% response rate for facial wrinkles5,7 
  5. 94% response rate for improvement in the appearance of cellulite4,7,8
  6. Reduces the appearance of cellulite severity with only one non-surgical treatment4,8,9
  7. The only real-time, temperature-controlled RF microneedling device4
  8. Proven in 8 comprehensive clinical studies10
Before and Afters

The Profound treatment reduces the signs of aging to create younger, smoother-looking skin.2,4,5,11


  • Before
    Steve Eubanks, MD
Leverage these valuable marketing insights.
Icon illustrating that 1.7 million American adults age 19-50 had non-surgical aesthetic procedures in 2017.

1.7 million

American adults age 19-50 had non-surgical aesthetic procedures in 201712

Icon illustrating the fact that $23 million was spent on non-surgical cellulite treatments in 2017.

$23 million

spent on non-surgical cellulite treatments in 201712

Icon illustrating that $6.84 billion was spent on skin rejuvenation, injectables, and other non-surgical procedures in 2016.

$6.84 billion

spent on skin rejuvenation, injectables, and other non-surgical procedures in 201613

Ready to boost your ROI?

Discover all the ways the Profound system can help your practice grow. Contact a Profound system expert now.


Product Specifications

Bi-polar Radio Frequency460 ± 5 kHz
Maximum Output Voltage84 VRMS; 5W per channel
Channels5 independent bi-polar channels
ModePID temperature control
Target Temperature Range65-75˚C (149 – 167˚F) ± 1˚C
Treatment Duration3-5 seconds, 0.2 second increments
User InterfaceGUI – color touch screen
System Dimensions125 x 46.5 x 44.5 centimeters
29.5 x 18.5 x 17.5 inches
System Weight23 kg / 55 lbs
Electrical Requirements100 – 240 VAC; 2.5 A; 50-60 Hz; single phase


  1. Hantash BM, Ubeid AA, Chang H, Kafi R, Renton B. Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis. Lasers Surg Med. 2009;41(1):1-9. 
  2. Willey A, Kilmer S, Newman J, et al. Elastometry and clinical results after bipolar radiofrequency treatment of skin. Dermatol Surg. 2010;36(6):877-884. 
  3. Howard D. Structural changes associated with aging skin. The International Dermal Institute website. Available at: Structural_Changes_AssociatAs_with_Aging_Skin.html. 
  4. Profound 510(k) clearance (K161043), September 2016. 
  5. Alexiades-Armenakas M, Newman J, Willey A, et al. Prospective multicenter clinical trial of a minimally invasive temperature-controlled bipolar fractional radiofrequency system for rhytid and laxity treatment. Dermatol Surg. 2013;39(2):263-273. 
  6. Alexiades M, Berube D. Randomized, blinded, 3-arm clinical trial assessing optimal temperature and duration for treatment with minimally invasive fractional radiofrequency. Dermatol Surg. 2015;41(5):623-632. 
  7. Data on file. Individual results may vary.
  8. Rate for independent thigh assessment. Patients with Fitzpatrick skin types I-III were assessed for improvement in dimples and undulation irregularities. The mean pain level reported was 3.74 on a 10-point scale. Anticipated treatment responses such as erythema and edema were reported and were completely resolved without medical intervention.4  
  9. Alexiades M, Munavalli G, Goldberg D, Berube D. Prospective multicenter clinical trial of a temperature-controlled subcutaneous microneedle fractional bipolar radiofrequency system for the treatment of cellulite. Dermatol Surg. 2018;1-10. doi: 10.1097. 
  10. Candela, data on file.
  11. Berube D. How Profound effectively treats cellulite via collagenesis and elastogenesis. 2016.
  12. American Society for Aesthetic Plastic Surgery. 2017 Cosmetic Surgery National Data Bank Statistics. 
  13. American Society for Aesthetic Plastic Surgery. 2016 Cosmetic Surgery National Data Bank Statistics.