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What eTwo is For

2 unique applications in 1 desktop platform for ablation, resurfacing, and wrinkles.1,2

The Sublime™ handpiece provides a non-invasive wrinkle treatment. It uses the elōs® system to combine levels of infrared (IR) light and bi-polar radio frequency (RF) energies to remodel the deep dermal layer of the skin by stimulating new collagen growth. 

This predictable heating of the deep dermis stimulates and shortens aged collagen fibers, resulting in immediate and long-term improvement of wrinkles.

Photo of woman’s face receiving treatment from the eTwo device and Sublative iD focal tip for wrinkle reduction.

The Sublative™ applicator

A new category of fractional skin treatments. 

Its fractionated bi-polar RF technology uses heat energy to encourage significant increases of collagen and elastin in the upper dermis - with low epidermal disruption for a broad range of skin types. 

Less affected tissue surrounding the matrix points may be stimulated by heat, which helps accelerate the healing process, leading to a smoother, rejuvenated appearance of the skin. 

Photo of woman’s face with fresh-looking and clear skin.

The power of eTwo

The Sublime and Sublative applicators combined.1,2  

eTwo, you can even perform a combination facial treatment to achieve dermal remodeling and textural improvement at the same time.

Photo of smiling woman speaking with her doctor about facial rejuvenation through treatment of wrinkles with eTwo device.

Rejuvenate your patients.

The eTwo system for skin rejuvenation through the treatment of wrinkles can help you deliver what patients value most. 

Visible results.

In a multi-center study of 72 subjects, the majority experienced improvement in wrinkle reduction and overall facial appearance.

Sublative + Sublime treatments in on ROI-boosting system.
Graphic illustrating over 70% of patients reported wrinkle reduction.

Over 70%

achieved wrinkle reduction2

Graphic illustrating over 90% percent of patients showed improvement in overall facial appearance.

Over 90%

improved overall facial appearance2

Invigorate Your Practice with eTwo

The eTwo system offers your practice optimal ROI potential, with:

  • Low acquisition and disposable costs
  • The ability to add non-invasive wrinkle treatments to your revenue stream 
  • Unparalleled support from the global leaders in the aesthetic medical device marketplace 
Get everything but the kitchen sink. In less space than a kitchen towel.


  • The eTwo system’s 15-inch touchscreen makes it easy to transform your patients’ skin.
  • Tissue light and RF effect illustration to display relative depth of penetration into skin of light and RF energies


  • Customizable settings to ensure the best treatment outcomes for your patients
  • Full energy selection bar with highlighted program change


  • Intelligent Feedback Graph (IFG) shows a moving average of pulse-to-pulse impedance
  • Skin Feedback Meter (SFM) indicates skin condition and energy delivered
  • Full energy selection bar with highlighted program change
  • Scaled injury pattern shows depth and width of sublative thermal damage

Sublative iD Focal Tip

Increase your capabilities, not your investment. Add the Sublative iD™ Focal Tip. 

This all-new tip features a compact design to treat smaller areas, including nasolabial folds and around the periorbital rim. 

Smaller surface area 
(11 x 3 mm) for focused treatment

44 pins, 200 pulses 
for optimal coverage 

Re-connectable design3 
to maximize your return on investment 

The demand for facial rejuvenation is rising.
Icon displaying the 18 million women who are interested in non-surgical treatment.

18 million

women are interested in a non-surgical treatment4

Icon displaying 9 million women are the potential market for high-end facial treatments.

9 million

women are the potential market for high-end facial treatments4

Icon displaying high demand for wrinkle treatments.

52 million

estimated patients for wrinkle treatments5,6

The eTwo system is the right tool at the right time to seize the opportunity.

Let a Candela product expert show you how you and eTwo can achieve great results for your patients and a high ROI for your practice.


In The Media
Sublative | XO Jane
Blogger Kathleen Braine ("XO Jane") shares her Sublative experience for the treatment of acne scars in NYC.
In The Media
My Face My Body Awards Australasia 2015
Congratulations to Syneron Candela ANZ! WINNER of My Face and My Body Awards Australasia 2015 "The Best Customer Service by a Manufacturer or Supplier" and HIGHLY COMMENDED for "Complete Facial

Product Specifications

Sublative EnergyUp to 100 mJ/pin
Sublime EnergyUp to 200 J/cm3
Sublime Spot Size12 x 8 mm
Sublative iD Spot SizeStandard 64 - 12 x 12 mm
Focal 44 - 11 x 3 mm
Disposable Sublative iD Standard 64 up to 400 pulses
Focal 44 up to 200 pulses
User Interface15" touch screen
System Dimensions Table Top53 x 30 x 40 cm
21.8” x 11.8” x 15.7”
System Weight8.5 kg / 18.7 lbs
Electrical Requirements100-240 VAC; 3A; 50-60 Hz


  1. elōs Plus 510(k) clearance for dermatologic procedures including removal of unwanted hair, treatment of vascular lesions, wrinkles, superficial benign vascular and pigmented lesions, and acne vulgaris, (K113868), June 2012. 
  2. eTwo 510(k) clearance for Sublative RF skin ablation and resurfacing and Sublime for wrinkles (K141507), Dec. 2014. 
  3. To help ensure patient health, re-connectable tips should not be used on more than one patient.
  4. Syneron Candela proprietary online consumer survey 2015
  5. 2013 U.S. Census Bureau, Population Division, June 2014.
  6. Internal Syneron Candela estimation.